Wednesday, October 10, 2007

IN MY VIEW: Proposed FDA Tobacco Product Safety Standards Make No Sense, and Have No Confirmed Connection with Safety

Here is a challenge question for everyone out there.

Below are two lists of chemical ingredients in cigarettes and tobacco smoke. The first list is a partial, current list of ingredients and constituents. The second list is the same, but has 20 hazardous chemicals removed.

In a sense, this is a simulation of what the proposed strategy that is being promoted to make cigarettes safer through the FDA legislation would look like. The FDA would be given the authority to choose specific ingredients and require their reduction or elimination.

Let us assume, under a best case scenario, that the FDA is able to get through regulations that would eliminate 20 of the hazardous chemicals in cigarettes.

Here is the question:

How much safer is the second group of chemicals than the first group? What would the relative risk for lung cancer be if cigarettes contained the second list of chemicals, rather than the first list? How about the relative risk for emphysema? The relative risk for heart disease?

Since the anti-smoking groups supporting the FDA legislation claim that the bill would require cigarette companies to make their products safer, I assume that they will be able to answer this question.

I'll give these groups until Friday to respond. I'll report back on Friday with the responses that I receive.

How much safer will cigarettes be if we can knock out a whopping 20 of the hazardous ingredients?

List #1
Acetanisole, · Acetic Acid, · Acetoin, · Acetophenone, · 6-Acetoxydihydrotheaspirane, · 2-Acetyl-3- Ethylpyrazine, · 2-Acetyl-5-Methylfuran, · Acetylpyrazine, · 2-Acetylpyridine, · 3-Acetylpyridine, · 2-Acetylthiazole, · Aconitic Acid, · dl-Alanine, · Alfalfa Extract, · Allspice Extract, · Oleoresin, · And Oil, · Allyl Hexanoate, · Allyl Ionone, · Almond Bitter Oil, · Ambergris Tincture, · Ammonia, · Ammonium Bicarbonate, · Ammonium Hydroxide, · Ammonium Phosphate Dibasic, · Ammonium Sulfide, · Amyl Alcohol, · Amyl Butyrate, · Amyl Formate, · Amyl Octanoate, · alpha-Amylcinnamaldehyde, · Amyris Oil, · trans-Anethole, · Angelica Root Extract, Oil and Seed Oil, · Anise, · Anise Star, Extract and Oils, · Anisyl Acetate, · Anisyl Alcohol, · Anisyl Formate, · Anisyl Phenylacetate, · Apple Juice Concentrate, Extract, and Skins, · Apricot Extract and Juice Concentrate, · 1-Arginine, · Asafetida Fluid Extract And Oil, · Ascorbic Acid, · 1-Asparagine Monohydrate, · 1-Aspartic Acid, · Balsam Peru and Oil, · Basil Oil, · Bay Leaf, Oil and Sweet Oil, · Beeswax White, · Beet Juice Concentrate, · Benzaldehyde, · Benzaldehyde Glyceryl Acetal, · Benzoic Acid, Benzoin, · Benzoin Resin, · Benzophenone, · Benzyl Alcohol, · Benzyl Benzoate, · Benzyl Butyrate, · Benzyl Cinnamate, · Benzyl Propionate, · Benzyl Salicylate, · Bergamot Oil, · Bisabolene, · Black Currant Buds Absolute, · Borneol, · Bornyl Acetate, · Buchu Leaf Oil, · 1,3-Butanediol, · 2,3-Butanedione, · 1-Butanol, · 2-Butanone, · 4(2-Butenylidene)-3,5,5-Trimethyl-2-Cyclohexen-1-One, · Butter, Butter Esters, and Butter Oil, · Butyl Acetate, · Butyl Butyrate, · Butyl Butyryl Lactate, · Butyl Isovalerate, · Butyl Phenylacetate, · Butyl Undecylenate, · 3-Butylidenephthalide, · Butyric Acid, · Cadinene, · Caffeine, · Calcium Carbonate, · Camphene, · Cananga Oil, · Capsicum Oleoresin, · Caramel Color, · Caraway Oil, · Carbon Dioxide, · Cardamom Oleoresin, Extract, Seed Oil, and Powder, · Carob Bean and Extract, · beta-Carotene, · Carrot Oil, · Carvacrol, · 4-Carvomenthenol, · 1-Carvone, · beta-Caryophyllene, · beta-Caryophyllene Oxide, · Cascarilla Oil and Bark Extract, · Cassia Bark Oil, · Cassie Absolute and Oil, · Castoreum Extract, Tincture and Absolute, · Cedar Leaf Oil, · Cedarwood Oil Terpenes and Virginiana, · Cedrol, · Celery Seed Extract, Solid, Oil, And Oleoresin, · Cellulose Fiber, · Chamomile Flower Oil And Extract, · Chicory Extract, · Chocolate, · Cinnamaldehyde, · Cinnamic Acid, · Cinnamon Leaf Oil, Bark Oil, and Extract, · Cinnamyl Acetate, · Cinnamyl Alcohol, · Cinnamyl Cinnamate, · Cinnamyl Isovalerate, · Cinnamyl Propionate, · Citral, · Citric Acid, · Citronella Oil, · dl-Citronellol, · Citronellyl Butyrate, · Citronellyl Isobutyrate, · Civet Absolute, · Clary Oil, · Clover Tops, Red Solid Extract, · Cocoa, · Cocoa Shells, Extract, Distillate And Powder, · Coconut Oil, · Coffee, · Cognac White and Green Oil, · Copaiba Oil, · Coriander Extract and Oil, · Corn Oil, · Corn Silk, · Costus Root Oil, · Cubeb Oil, · Cuminaldehyde, · para-Cymene, · 1-Cysteine, · Dandelion Root Solid Extract, · Davana Oil, · 2-trans, 4-trans-Decadienal, · delta-Decalactone, · gamma-Decalactone, · Decanal, · Decanoic Acid, · 1-Decanol, · 2-Decenal, · Dehydromenthofurolactone, · Diethyl Malonate, · Diethyl Sebacate, · 2,3-Diethylpyrazine, · Dihydro Anethole, · 5,7-Dihydro-2-Methylthieno(3,4-D) Pyrimidine, · Dill Seed Oil and Extract, · meta-Dimethoxybenzene, · para-Dimethoxybenzene, · 2,6-Dimethoxyphenol, · Dimethyl Succinate, · 3,4-Dimethyl-1,2-Cyclopentanedione, · 3,5- Dimethyl-1,2-Cyclopentanedione, · 3,7-Dimethyl-1,3,6-Octatriene, · 4,5-Dimethyl-3-Hydroxy-2,5-Dihydrofuran-2-One, · 6,10-Dimethyl-5,9-Undecadien-2-One, · 3,7-Dimethyl-6-Octenoic Acid, · 2,4-Dimethylacetophenone, · alpha,para-Dimethylbenzyl Alcohol, · alpha,alpha-Dimethylphenethyl Acetate, · alpha,alpha Dimethylphenethyl Butyrate, · 2,3-Dimethylpyrazine, · 2,5-Dimethylpyrazine, · 2,6-Dimethylpyrazine, · Dimethyltetrahydrobenzofuranone, · delta-Dodecalactone, · gamma-Dodecalactone, · para-Ethoxybenzaldehyde, · Ethyl 10-Undecenoate, · Ethyl 2-Methylbutyrate, · Ethyl Acetate, · Ethyl Acetoacetate, · Ethyl Alcohol, · Ethyl Benzoate, · Ethyl Butyrate, · Ethyl Cinnamate, · Ethyl Decanoate, · Ethyl Fenchol, · Ethyl Furoate, · Ethyl Heptanoate, · Ethyl Hexanoate, · Ethyl Isovalerate, · Ethyl Lactate, · Ethyl Laurate, · Ethyl Levulinate, · Ethyl Maltol, · Ethyl Methyl Phenylglycidate, · Ethyl Myristate, · Ethyl Nonanoate, · Ethyl Octadecanoate, · Ethyl Octanoate, · Ethyl Oleate, · Ethyl Palmitate, · Ethyl Phenylacetate, · Ethyl Propionate, · Ethyl Salicylate, · Ethyl trans-2-Butenoate, · Ethyl Valerate, · Ethyl Vanillin, · 2-Ethyl (or Methyl)-(3,5 and 6)-Methoxypyrazine, · 2-Ethyl-1-Hexanol, 3-Ethyl -2 -Hydroxy-2-Cyclopenten-1-One, · 2-Ethyl-3, (5 or 6)-Dimethylpyrazine, · 5-Ethyl-3-Hydroxy-4-Methyl-2(5H)-Furanone, · 2-Ethyl-3-Methylpyrazine, · 4-Ethylbenzaldehyde, · 4-Ethylguaiacol, · para-Ethylphenol, · 3-Ethylpyridine, · Eucalyptol, · Farnesol, · D-Fenchone, · Fennel Sweet Oil, · Fenugreek, Extract, Resin, and Absolute, · Fig Juice Concentrate, · Food Starch Modified, · Furfuryl Mercaptan, · 4-(2-Furyl)-3-Buten-2-One, · Galbanum Oil, · Genet Absolute, · Gentian Root Extract, · Geraniol, · Geranium Rose Oil, · Geranyl Acetate, · Geranyl Butyrate, · Geranyl Formate, · Geranyl Isovalerate, · Geranyl Phenylacetate, · Ginger Oil and Oleoresin, · 1-Glutamic Acid, · 1-Glutamine, · Glycerol, · Glycyrrhizin Ammoniated, · Grape Juice Concentrate, · Guaiac Wood Oil, · Guaiacol, · Guar Gum, · 2,4-Heptadienal, · gamma-Heptalactone, · Heptanoic Acid, · 2-Heptanone, · 3-Hepten-2-One, · 2-Hepten-4-One, · 4-Heptenal, · trans -2-Heptenal, · Heptyl Acetate, · omega-6-Hexadecenlactone, · gamma-Hexalactone, · Hexanal, · Hexanoic Acid, · 2-Hexen-1-Ol, · 3-Hexen-1-Ol, · cis-3-Hexen-1-Yl Acetate, · 2-Hexenal, · 3-Hexenoic Acid, · trans-2-Hexenoic Acid, · cis-3-Hexenyl Formate, · Hexyl 2-Methylbutyrate, · Hexyl Acetate, · Hexyl Alcohol, · Hexyl Phenylacetate, · 1-Histidine, · Honey, · Hops Oil, · Hydrolyzed Milk Solids, · Hydrolyzed Plant Proteins, · 5-Hydroxy-2,4-Decadienoic Acid delta- Lactone, · 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone, · 2-Hydroxy-3,5,5-Trimethyl-2-Cyclohexen-1-One, · 4-Hydroxy -3-Pentenoic Acid Lactone, · 2-Hydroxy-4-Methylbenzaldehyde, · 4-Hydroxybutanoic Acid Lactone, · Hydroxycitronellal, · 6-Hydroxydihydrotheaspirane, · 4-(para-Hydroxyphenyl)-2-Butanone, · Hyssop Oil, · Immortelle Absolute and Extract, · alpha-Ionone, · beta-Ionone, · alpha-Irone, · Isoamyl Acetate, · Isoamyl Benzoate, · Isoamyl Butyrate, · Isoamyl Cinnamate, · Isoamyl Formate, Isoamyl Hexanoate, · Isoamyl Isovalerate, · Isoamyl Octanoate, · Isoamyl Phenylacetate, · Isobornyl Acetate, · Isobutyl Acetate, · Isobutyl Alcohol, · Isobutyl Cinnamate, · Isobutyl Phenylacetate, · Isobutyl Salicylate, · 2-Isobutyl-3-Methoxypyrazine, · alpha-Isobutylphenethyl Alcohol, · Isobutyraldehyde, · Isobutyric Acid, · d,l-Isoleucine, · alpha-Isomethylionone, · 2-Isopropylphenol, · Isovaleric Acid, · Jasmine Absolute, Concrete and Oil, · Kola Nut Extract, · Labdanum Absolute and Oleoresin, · Lactic Acid, · Lauric Acid, · Lauric Aldehyde, · Lavandin Oil, · Lavender Oil, · Lemon Oil and Extract, · Lemongrass Oil, · 1-Leucine, · Levulinic Acid, · Licorice Root, Fluid, Extract and Powder, · Lime Oil , · Linalool, · Linalool Oxide, · Linalyl Acetate, · Linden Flowers, · Lovage Oil And Extract, · 1-Lysine, · Mace Powder, Extract and Oil , · Magnesium Carbonate, · Malic Acid, · Malt and Malt Extract, · Maltodextrin, · Maltol, · Maltyl Isobutyrate, · Mandarin Oil, · Maple Syrup and Concentrate, · Mate Leaf, Absolute and Oil, · para-Mentha-8-Thiol-3-One, · Menthol, · Menthone, · Menthyl Acetate, · dl-Methionine, · Methoprene, · 2-Methoxy-4-Methylphenol, · 2-Methoxy-4-Vinylphenol, · para-Methoxybenzaldehyde, · 1-(para-Methoxyphenyl)-1-Penten-3-One, · 4-(para-Methoxyphenyl)-2-Butanone, · 1-(para-Methoxyphenyl)-2-Propanone, · Methoxypyrazine, · Methyl 2-Furoate, · Methyl 2-Octynoate, · Methyl 2-Pyrrolyl Ketone, · Methyl Anisate, · Methyl Anthranilate, · Methyl Benzoate, · Methyl Cinnamate, · Methyl Dihydrojasmonate, · Methyl Ester of Rosin, Partially Hydrogenated, · Methyl Isovalerate, · Methyl Linoleate (48%), · Methyl Linolenate (52%) Mixture, · Methyl Naphthyl Ketone, · Methyl Nicotinate, · Methyl Phenylacetate, · Methyl Salicylate, · Methyl Sulfide, · 3-Methyl-1-Cyclopentadecanone, · 4-Methyl-1-Phenyl-2-Pentanone, · 5-Methyl-2-Phenyl-2-Hexenal, · 5-Methyl-2-Thiophenecarboxaldehyde, · 6-Methyl-3,-5-Heptadien-2-One, · 2-Methyl-3-(para-Isopropylphenyl) Propionaldehyde, · 5-Methyl-3-Hexen-2-One, · 1-Methyl-3Methoxy-4-Isopropylbenzene, · 4-Methyl-3-Pentene-2-One, · 2-Methyl-4-Phenylbutyraldehyde, · 6-Methyl-5-Hepten-2-One, · 4-Methyl-5-Thiazoleethanol, · 4-Methyl-5-Vinylthiazole, · Methyl-alpha-Ionone, · Methyl-trans-2-Butenoic Acid, · 4-Methylacetophenone, · para-Methylanisole, · alpha-Methylbenzyl Acetate, · alpha-Methylbenzyl Alcohol, · 2-Methylbutyraldehyde, · 3-Methylbutyraldehyde, · 2-Methylbutyric Acid, · alpha-Methylcinnamaldehyde, · Methylcyclopentenolone, · 2-Methylheptanoic Acid, · 2-Methylhexanoic Acid, · 3-Methylpentanoic Acid, · 4-Methylpentanoic Acid, · 2-Methylpyrazine, · 5-Methylquinoxaline, · 2-Methyltetrahydrofuran-3-One * (Methylthio)Methylpyrazine (Mixture Of Isomers), · 3-Methylthiopropionaldehyde, · Methyl 3-Methylthiopropionate, · 2-Methylvaleric Acid, · Mimosa Absolute and Extract, · Molasses Extract and Tincture, · Mountain Maple Solid Extract, · Mullein Flowers, · Myristaldehyde, · Myristic Acid, · Myrrh Oil, · beta-Napthyl Ethyl Ether, · Nerol, · Neroli Bigarde Oil, · Nerolidol, · Nona-2-trans,6-cis-Dienal, · 2,6-Nonadien-1-Ol, · gamma-Nonalactone, · Nonanal, · Nonanoic Acid, · Nonanone, · trans-2-Nonen-1-Ol, · 2-Nonenal, · Nonyl Acetate, · Nutmeg Powder and Oil, · Oak Chips Extract and Oil, · Oak Moss Absolute, · 9,12-Octadecadienoic Acid (48%) And 9,12,15-Octadecatrienoic Acid (52%), · delta-Octalactone, · gamma-Octalactone, · Octanal, · Octanoic Acid, · 1-Octanol, · 2-Octanone, · 3-Octen-2-One, · 1-Octen-3-Ol, · 1-Octen-3-Yl Acetate, · 2-Octenal, · Octyl Isobutyrate, · Oleic Acid , · Olibanum Oil, · Opoponax Oil And Gum, · Orange Blossoms Water, Absolute, and Leaf Absolute, · Orange Oil and Extract, · Origanum Oil, · Orris Concrete Oil and Root Extract, · Palmarosa Oil, · Palmitic Acid, · Parsley Seed Oil, · Patchouli Oil, · omega-Pentadecalactone, · 2,3-Pentanedione, · 2-Pentanone, · 4-Pentenoic Acid, · 2-Pentylpyridine, · Pepper Oil, Black And White, · Peppermint Oil, · Peruvian (Bois De Rose) Oil, · Petitgrain Absolute, Mandarin Oil and Terpeneless Oil, · alpha-Phellandrene, · 2-Phenenthyl Acetate, · Phenenthyl Alcohol, · Phenethyl Butyrate, · Phenethyl Cinnamate, · Phenethyl Isobutyrate, · Phenethyl Isovalerate, · Phenethyl Phenylacetate, · Phenethyl Salicylate, · 1-Phenyl-1-Propanol, · 3-Phenyl-1-Propanol, · 2-Phenyl-2-Butenal, · 4-Phenyl-3-Buten-2-Ol, · 4-Phenyl-3-Buten-2-One, · Phenylacetaldehyde, · Phenylacetic Acid, · 1-Phenylalanine, · 3-Phenylpropionaldehyde, · 3-Phenylpropionic Acid, · 3-Phenylpropyl Acetate, · 3-Phenylpropyl Cinnamate, · 2-(3-Phenylpropyl)Tetrahydrofuran, · Phosphoric Acid, · Pimenta Leaf Oil, · Pine Needle Oil, Pine Oil, Scotch, · Pineapple Juice Concentrate, · alpha-Pinene, beta-Pinene, · D-Piperitone, · Piperonal, · Pipsissewa Leaf Extract, · Plum Juice, · Potassium Sorbate, · 1-Proline, · Propenylguaethol, · Propionic Acid, · Propyl Acetate, · Propyl para-Hydroxybenzoate, · Propylene Glycol, · 3-Propylidenephthalide, · Prune Juice and Concentrate, · Pyridine, · Pyroligneous Acid And Extract, * * Pyrrole, * Pyruvic Acid, * Raisin Juice Concentrate, * Rhodinol, * Rose Absolute and Oil, * Rosemary Oil, * Rum, * Rum Ether, * Rye Extract, * Sage, Sage Oil, and Sage Oleoresin, * Salicylaldehyde, * Sandalwood Oil, Yellow, * Sclareolide, * Skatole, * Smoke Flavor, * Snakeroot Oil, * Sodium Acetate, * Sodium Benzoate, * Sodium Bicarbonate, * Sodium Carbonate, * Sodium Chloride, * Sodium Citrate, * Sodium Hydroxide, * Solanone, * Spearmint Oil, * Styrax Extract, Gum and Oil, * Sucrose Octaacetate, * Sugar Alcohols, * Sugars, * Tagetes Oil, * Tannic Acid, * Tartaric Acid, * Tea Leaf and Absolute, * alpha-Terpineol, * Terpinolene, * Terpinyl Acetate, * 5,6,7,8-Tetrahydroquinoxaline, * 1,5,5,9-Tetramethyl-13-Oxatricyclo(8.3.0.0(4,9))Tridecane, * 2,3,4,5, and 3,4,5,6-Tetramethylethyl-Cyclohexanone, * 2,3,5,6-Tetramethylpyrazine, * Thiamine Hydrochloride, * Thiazole, * 1-Threonine, * Thyme Oil, White and Red, * Thymol, * Tobacco Extracts, * Tochopherols (mixed), * Tolu Balsam Gum and Extract, * Tolualdehydes, * para-Tolyl 3-Methylbutyrate, * para-Tolyl Acetaldehyde, * para-Tolyl Acetate, * para-Tolyl Isobutyrate, * para-Tolyl Phenylacetate, * Triacetin, * 2-Tridecanone, * 2-Tridecenal, * Triethyl Citrate, * 3,5,5-Trimethyl -1-Hexanol, * para,alpha,alpha-Trimethylbenzyl Alcohol, * 4-(2,6,6-Trimethylcyclohex-1-Enyl)But-2-En-4-One, * 2,6,6-Trimethylcyclohex-2-Ene-1,4-Dione, * 2,6,6-Trimethylcyclohexa-1,3-Dienyl Methan, * 4-(2,6,6-Trimethylcyclohexa-1,3-Dienyl)But-2-En-4-One, * 2,2,6-Trimethylcyclohexanone, * 2,3,5-Trimethylpyrazine, * 1-Tyrosine, * delta-Undercalactone, * gamma-Undecalactone, * Undecanal, * 2-Undecanone, 1 * 0-Undecenal, * Urea, * Valencene, * Valeraldehyde, * Valerian Root Extract, Oil and Powder, * Valeric Acid, * gamma-Valerolactone, * Valine, * Vanilla Extract And Oleoresin, * Vanillin, * Veratraldehyde, * Vetiver Oil, * Vinegar, * Violet Leaf Absolute, * Walnut Hull Extract, * Water, * Wheat Extract And Flour, * Wild Cherry Bark Extract, * Wine and Wine Sherry, * Xanthan Gum, * 3,4-Xylenol, * Yeast Benzene 2-Napthylamine 4-Aminobiphenyl Nickel Polonium 210 (radioactive) Nitrogen oxides N-Nitrosodimethylamine N-Nitrosodiethylamine N-Nitrosopyrrolidine 1,3-Butadiene Analine Formaldehyde Hydrazine N-Nitrodiethanolamine Cadmium Benzo[a]pyrene Benz[a]anthracene Y-Butyrolactone Particulate matter N-Nitrosonornicotine NNK Carbon monoxide Carbon dioxide Carbonyl sulfide Toluene Acrolein Acetone Pyridine 3-Methylpyridine 3-Vinylpyridine Hydrogen cyanide Ammonia Methylamine Dimethylamine Nicotine Anatabine Phenol Catechol Hydorquinone Cholesterol Quinoline Harman Zinc Benzoic acid Lactic acid Glycolic acid Succinic acit PCDDs and PCDFs (Dioxins, Dibenzofurans) Formic acid Acetic acid Methyl chloride Dimethylnitrosamine Ethylmethylnitrosamine Nitrosopyrrolidine Hydrazine Vinyl Chloride Urethane Formaldehyde Carbon Monoxide Hydrogen Cyanide Acrolein Acetadehyde Nitrogen oxides Ammonia Pyridine Nitric acid Mathylamine Hydrogen cyanide Indole 3-hydroxypyridine 3-vinylpyridine Acetone Acetonitrile Acrolein 1,3-Butadiene, mg Nitrous acid isoquioline Isoamylamine 3-Cyanopyridine Carbonyls Formaldehyde, Acetaldehyde, Acetone, Acrolein, Propionaldehyde, Crotonaldehyde, Methyl-Ethyl-Ketone, Butyraldehyde Phenolics Hydroquinone, Resorcinol, Catechol, Phenol, Cresol (m+p and o) Benzo[a]pyrene BaP (HPLC) Aromatic Amines 3- and 4-aminobiphenyl, 1- and 2- aminonapthlene, o-toluidine, o-anisidine Oxides of Nitrogen NO, NOx Hydrogen Cyanide HCN (gas and particulate phases) Ammonia NH3 by ion chromatography Volatiles Benzene, Toluene, 1,3-butadiene, Isoprene, Acrylonitrile Semi-Volatiles Pyridine, Quinoline, Styrene Trace Metals Nickel (Ni) Cadmium (Cd) Lead (Pb) Chromium (Cr) Arsenic (As) Selenium (Se) Mercury Mercury (Hg) Smoke pH Integrated Puff Profile Tobacco Specific Nitrosamines N-Nitrosonornicotine (NNN) N-Nitrosoanabasine (NAB) N-Nitrosoanatabine (NAT) 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) Volatile Nitrosamines N,N-Nitrosodimethylamine (NDMA) N-Nitrosopyrrolidine (NPYR) N,N-Nitrosodiethylamine (NDEA) N,N-Nitrosoethylmethylamine (NEMA) N,N-Nitrosodipropylamine (NDPA) N,N-Nitrosodibuthylamine (NDBA) N-Nitrosopiperidine (NPIP) Polycyclic Aromatic Hydrocarbons Naphthalene 1-Methylnaphthalene 2-methylnaphthalene Acenaphthylene Acenaphthene Fluorene Phenanthrene Anthracene Fluoranthene Pyrene Benzo(a)anthracene Chrysene Benzo(b)fluoranthene Benzo(k)fluoranthene Benzo(j)fluoranthene Benzo(g,h,l)perylene Benzo(e)pyrene Benzo(a)pyrene Perylene Indeno(1,2,3,-cd)pyrene Dibenzo(a,h)anthracene Dibenz(a,j)acridine Dibenz(a,h)acridine Dibenz(a,e)pyrene Dibenz(a,h)pyrene Dibenz(a,i)pyrene Dibenz(a,l)pyrene 7H-Dibenzo(c,g)carbazole Heterocyclic Aromatic Amines 2-Amino-3-methylimidaszo(4,5-f)quinoline (IQ) 2-Amino-3,4-dimethylimidazo(4,5-f)quinoline (MeIQ) 2-Amino-3-methyl-9H-pyrido(2,3-b)indole (MeAaC) 2-Amino-9H-pyrido(2,3-b)indole (AaC) 1-Methyl-9H-pyridol(3,4-b)indole (Harman) 9H-Pyrido(3,4-b)indole (Norharman) Nitrogen 280-320 mg (56-64%b) Oxygen 50-70 mg (11-14%b) Carbon dioxide 45-65 mg (9-13%b) Carbon monoxide 14-23 mg (2.8-4.6%b) Water 7-12 mg (1.4-2.4%b) Argon 5mg (1.0%b) Hydrogen 0.5-1.0 mg Ammonia 10-130 μg Nitrogen oxides (NOx) 100-600 μg Hydrogen cyanide 400-500 μg Hydrogen sulfide 20-90 μg Methane 1.0-2.0 mg Other volatile alkanes (20) 1.0-.16 mgc Volatile alkenes (16) 0.4-0.5mg Isoprene 0.2-0.4mg Butadiene 25-40μg Acetylene 20-35μg Benzene 12-50μg Toluene 20-60μg Styrene 10μg Other volatile aromatic hydrocarbons (29) 15-30μg Formic acid 200-600 μg Acetic acid 300-1,700 μg Propionic acid 100-300 μg Methyl formate 20-30 μg Other volatile acids (6) 5-10 μgc Formaldehyde 20-100 μg Acetaldehyde 400-1,400 μg Acrolein 60-140 μg Other volatile aldehydes (6) Acetone Other volatile ketones (3) Methanol Other volatile alcohols (7) Acetonitrile Other volatile nitriles (I0) Furan Other volatile furans (4) Pyridine Picolines (3) 3-Vinylpyridine Other volatile pyridines (25) Pyrrole Pyrrolidine N-Methylpyrrolidine Volatile pyrazines (18) Methylamine Other aliphatic amines (32) Nornicotine Anatabine Anabasine Other tobacco alkaloids (17) Bipyridyls (4) n-Hentriacontane (n-C31H64) Total nonvolatile hydrocarbons (45)b Naphthalene Other naphthalenes (23) Phenanthrenes (7) Anthracenes (5) Fluorenes (7) Pyrenes (6) Fluoranthenes (5) Carcinogenic polynuclear aromatic hydrocarbons (11)c Phenol Other phenols (45)b Catechol Other catechols (4) Other dihydroxybenzenes (10) Scopoletin Other polyphenols (8)b Cyclotenes (10)b Quinones (7) Solanesol Neophytadienes (4) 200-350 Limonene 30-60 Other terpenes (200-250)b NA Palmitic acid 100-150 Stearic acid 50-75 Oleic acid 40-110 Linoleic acid 60-150 Linolenic acid 150-250 Lactic acid 60-80 Indole 10-15 Skatole 12-16 Other indoles (13) NA Quinolines (7) 2-4 Other N-heterocyclic hydrocarbons (55) NA Benzofurans (4) 200-300 Other O-heterocyclic hydrocarbons (42) NA Stigmasterol 40-70 Sitosterol 30-40 Campesterol 20-30 Cholesterol 10-20 Aniline 0.36 Toluidines 0.23 Other aromatic amines (12) 0.25 Tobacco-specific N-nitrosamines (4)c 0.34-2.7 Glycerol PAH Benz(a)anthracene Benzo(b)fluoranthene Benzo(j)fluoranthene Benzo(k)fluoranthene Benzo(a)pyrene Chrysene Dibenz(a,h)anthracene Dibenzo(a,1)pyrene Dibenzo(a,1)pyrene Indeno(1,2,3-c,d)pyrene 5-Methylchrysene Aza-arenes Quinoline Dibenz(a,h)acridine Dibenz(aj)acridine 7H-Dibenzo(c,g)carbazole N-Nitrosamines N-Nitrosodimethylamine N-Nitrosoethyl methylamine N-Nitrosodiethylamine N-Nitrosopyrrolidine N-Nitrosodiethanolamine N’-Nitrosonomicotine 4-(Methylnitrosamino)-1- (3-pyridyl)-1-butanone N’-Nitrosoanabasine N-Nitrosomorpholine 2-Toluidine 2-Naphthylamine 4-Aminobiphenyl Aldehydes Formaldehydea Acetaldehydea Crotonaldehyde Miscellaneous organic compounds Benzene Acrylonitrile 1,1-Dimethylhydrazine 2-Nitropropane Ethylcarbamate Vinylchloride Inorganic compounds Hydrazine Arsenic Nickel Chromium Cadmium Lead Polonium-210 Asbestos Plutonium

List #2
Acetanisole, · Acetic Acid, · Acetoin, · Acetophenone, · 6-Acetoxydihydrotheaspirane, · 2-Acetyl-3- Ethylpyrazine, · 2-Acetyl-5-Methylfuran, · Acetylpyrazine, · 2-Acetylpyridine, · 3-Acetylpyridine, · 2-Acetylthiazole, · Aconitic Acid, · dl-Alanine, · Alfalfa Extract, · Allspice Extract, · Oleoresin, · And Oil, · Allyl Hexanoate, · Allyl Ionone, · Almond Bitter Oil, · Ambergris Tincture, · Ammonia, · Ammonium Bicarbonate, · Ammonium Hydroxide, · Ammonium Phosphate Dibasic, · Ammonium Sulfide, · Amyl Alcohol, · Amyl Butyrate, · Amyl Formate, · Amyl Octanoate, · alpha-Amylcinnamaldehyde, · Amyris Oil, · trans-Anethole, · Angelica Root Extract, Oil and Seed Oil, · Anise, · Anise Star, Extract and Oils, · Anisyl Acetate, · Anisyl Alcohol, · Anisyl Formate, · Anisyl Phenylacetate, · Apple Juice Concentrate, Extract, and Skins, · Apricot Extract and Juice Concentrate, · 1-Arginine, · Asafetida Fluid Extract And Oil, · Ascorbic Acid, · 1-Asparagine Monohydrate, · 1-Aspartic Acid, · Balsam Peru and Oil, · Basil Oil, · Bay Leaf, Oil and Sweet Oil, · Beeswax White, · Beet Juice Concentrate, · Benzaldehyde, · Benzaldehyde Glyceryl Acetal, · Benzoic Acid, Benzoin, · Benzoin Resin, · Benzophenone, · Benzyl Alcohol, · Benzyl Benzoate, · Benzyl Butyrate, · Benzyl Cinnamate, · Benzyl Propionate, · Benzyl Salicylate, · Bergamot Oil, · Bisabolene, · Black Currant Buds Absolute, · Borneol, · Bornyl Acetate, · Buchu Leaf Oil, · 1,3-Butanediol, · 2,3-Butanedione, · 1-Butanol, · 2-Butanone, · 4(2-Butenylidene)-3,5,5-Trimethyl-2-Cyclohexen-1-One, · Butter, Butter Esters, and Butter Oil, · Butyl Acetate, · Butyl Butyrate, · Butyl Butyryl Lactate, · Butyl Isovalerate, · Butyl Phenylacetate, · Butyl Undecylenate, · 3-Butylidenephthalide, · Butyric Acid, · Cadinene, · Caffeine, · Calcium Carbonate, · Camphene, · Cananga Oil, · Capsicum Oleoresin, · Caramel Color, · Caraway Oil, · Carbon Dioxide, · Cardamom Oleoresin, Extract, Seed Oil, and Powder, · Carob Bean and Extract, · beta-Carotene, · Carrot Oil, · Carvacrol, · 4-Carvomenthenol, · 1-Carvone, · beta-Caryophyllene, · beta-Caryophyllene Oxide, · Cascarilla Oil and Bark Extract, · Cassia Bark Oil, · Cassie Absolute and Oil, · Castoreum Extract, Tincture and Absolute, · Cedar Leaf Oil, · Cedarwood Oil Terpenes and Virginiana, · Cedrol, · Celery Seed Extract, Solid, Oil, And Oleoresin, · Cellulose Fiber, · Chamomile Flower Oil And Extract, · Chicory Extract, · Chocolate, · Cinnamaldehyde, · Cinnamic Acid, · Cinnamon Leaf Oil, Bark Oil, and Extract, · Cinnamyl Acetate, · Cinnamyl Alcohol, · Cinnamyl Cinnamate, · Cinnamyl Isovalerate, · Cinnamyl Propionate, · Citral, · Citric Acid, · Citronella Oil, · dl-Citronellol, · Citronellyl Butyrate, · Citronellyl Isobutyrate, · Civet Absolute, · Clary Oil, · Clover Tops, Red Solid Extract, · Cocoa, · Cocoa Shells, Extract, Distillate And Powder, · Coconut Oil, · Coffee, · Cognac White and Green Oil, · Copaiba Oil, · Coriander Extract and Oil, · Corn Oil, · Corn Silk, · Costus Root Oil, · Cubeb Oil, · Cuminaldehyde, · para-Cymene, · 1-Cysteine, · Dandelion Root Solid Extract, · Davana Oil, · 2-trans, 4-trans-Decadienal, · delta-Decalactone, · gamma-Decalactone, · Decanal, · Decanoic Acid, · 1-Decanol, · 2-Decenal, · Dehydromenthofurolactone, · Diethyl Malonate, · Diethyl Sebacate, · 2,3-Diethylpyrazine, · Dihydro Anethole, · 5,7-Dihydro-2-Methylthieno(3,4-D) Pyrimidine, · Dill Seed Oil and Extract, · meta-Dimethoxybenzene, · para-Dimethoxybenzene, · 2,6-Dimethoxyphenol, · Dimethyl Succinate, · 3,4-Dimethyl-1,2-Cyclopentanedione, · 3,5- Dimethyl-1,2-Cyclopentanedione, · 3,7-Dimethyl-1,3,6-Octatriene, · 4,5-Dimethyl-3-Hydroxy-2,5-Dihydrofuran-2-One, · 6,10-Dimethyl-5,9-Undecadien-2-One, · 3,7-Dimethyl-6-Octenoic Acid, · 2,4-Dimethylacetophenone, · alpha,para-Dimethylbenzyl Alcohol, · alpha,alpha-Dimethylphenethyl Acetate, · alpha,alpha Dimethylphenethyl Butyrate, · 2,3-Dimethylpyrazine, · 2,5-Dimethylpyrazine, · 2,6-Dimethylpyrazine, · Dimethyltetrahydrobenzofuranone, · delta-Dodecalactone, · gamma-Dodecalactone, · para-Ethoxybenzaldehyde, · Ethyl 10-Undecenoate, · Ethyl 2-Methylbutyrate, · Ethyl Acetate, · Ethyl Acetoacetate, · Ethyl Alcohol, · Ethyl Benzoate, · Ethyl Butyrate, · Ethyl Cinnamate, · Ethyl Decanoate, · Ethyl Fenchol, · Ethyl Furoate, · Ethyl Heptanoate, · Ethyl Hexanoate, · Ethyl Isovalerate, · Ethyl Lactate, · Ethyl Laurate, · Ethyl Levulinate, · Ethyl Maltol, · Ethyl Methyl Phenylglycidate, · Ethyl Myristate, · Ethyl Nonanoate, · Ethyl Octadecanoate, · Ethyl Octanoate, · Ethyl Oleate, · Ethyl Palmitate, · Ethyl Phenylacetate, · Ethyl Propionate, · Ethyl Salicylate, · Ethyl trans-2-Butenoate, · Ethyl Valerate, · Ethyl Vanillin, · 2-Ethyl (or Methyl)-(3,5 and 6)-Methoxypyrazine, · 2-Ethyl-1-Hexanol, 3-Ethyl -2 -Hydroxy-2-Cyclopenten-1-One, · 2-Ethyl-3, (5 or 6)-Dimethylpyrazine, · 5-Ethyl-3-Hydroxy-4-Methyl-2(5H)-Furanone, · 2-Ethyl-3-Methylpyrazine, · 4-Ethylbenzaldehyde, · 4-Ethylguaiacol, · para-Ethylphenol, · 3-Ethylpyridine, · Eucalyptol, · Farnesol, · D-Fenchone, · Fennel Sweet Oil, · Fenugreek, Extract, Resin, and Absolute, · Fig Juice Concentrate, · Food Starch Modified, · Furfuryl Mercaptan, · 4-(2-Furyl)-3-Buten-2-One, · Galbanum Oil, · Genet Absolute, · Gentian Root Extract, · Geraniol, · Geranium Rose Oil, · Geranyl Acetate, · Geranyl Butyrate, · Geranyl Formate, · Geranyl Isovalerate, · Geranyl Phenylacetate, · Ginger Oil and Oleoresin, · 1-Glutamic Acid, · 1-Glutamine, · Glycerol, · Glycyrrhizin Ammoniated, · Grape Juice Concentrate, · Guaiac Wood Oil, · Guaiacol, · Guar Gum, · 2,4-Heptadienal, · gamma-Heptalactone, · Heptanoic Acid, · 2-Heptanone, · 3-Hepten-2-One, · 2-Hepten-4-One, · 4-Heptenal, · trans -2-Heptenal, · Heptyl Acetate, · omega-6-Hexadecenlactone, · gamma-Hexalactone, · Hexanal, · Hexanoic Acid, · 2-Hexen-1-Ol, · 3-Hexen-1-Ol, · cis-3-Hexen-1-Yl Acetate, · 2-Hexenal, · 3-Hexenoic Acid, · trans-2-Hexenoic Acid, · cis-3-Hexenyl Formate, · Hexyl 2-Methylbutyrate, · Hexyl Acetate, · Hexyl Alcohol, · Hexyl Phenylacetate, · 1-Histidine, · Honey, · Hops Oil, · Hydrolyzed Milk Solids, · Hydrolyzed Plant Proteins, · 5-Hydroxy-2,4-Decadienoic Acid delta- Lactone, · 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone, · 2-Hydroxy-3,5,5-Trimethyl-2-Cyclohexen-1-One, · 4-Hydroxy -3-Pentenoic Acid Lactone, · 2-Hydroxy-4-Methylbenzaldehyde, · 4-Hydroxybutanoic Acid Lactone, · Hydroxycitronellal, · 6-Hydroxydihydrotheaspirane, · 4-(para-Hydroxyphenyl)-2-Butanone, · Hyssop Oil, · Immortelle Absolute and Extract, · alpha-Ionone, · beta-Ionone, · alpha-Irone, · Isoamyl Acetate, · Isoamyl Benzoate, · Isoamyl Butyrate, · Isoamyl Cinnamate, · Isoamyl Formate, Isoamyl Hexanoate, · Isoamyl Isovalerate, · Isoamyl Octanoate, · Isoamyl Phenylacetate, · Isobornyl Acetate, · Isobutyl Acetate, · Isobutyl Alcohol, · Isobutyl Cinnamate, · Isobutyl Phenylacetate, · Isobutyl Salicylate, · 2-Isobutyl-3-Methoxypyrazine, · alpha-Isobutylphenethyl Alcohol, · Isobutyraldehyde, · Isobutyric Acid, · d,l-Isoleucine, · alpha-Isomethylionone, · 2-Isopropylphenol, · Isovaleric Acid, · Jasmine Absolute, Concrete and Oil, · Kola Nut Extract, · Labdanum Absolute and Oleoresin, · Lactic Acid, · Lauric Acid, · Lauric Aldehyde, · Lavandin Oil, · Lavender Oil, · Lemon Oil and Extract, · Lemongrass Oil, · 1-Leucine, · Levulinic Acid, · Licorice Root, Fluid, Extract and Powder, · Lime Oil , · Linalool, · Linalool Oxide, · Linalyl Acetate, · Linden Flowers, · Lovage Oil And Extract, · 1-Lysine, · Mace Powder, Extract and Oil , · Magnesium Carbonate, · Malic Acid, · Malt and Malt Extract, · Maltodextrin, · Maltol, · Maltyl Isobutyrate, · Mandarin Oil, · Maple Syrup and Concentrate, · Mate Leaf, Absolute and Oil, · para-Mentha-8-Thiol-3-One, · Menthol, · Menthone, · Menthyl Acetate, · dl-Methionine, · Methoprene, · 2-Methoxy-4-Methylphenol, · 2-Methoxy-4-Vinylphenol, · para-Methoxybenzaldehyde, · 1-(para-Methoxyphenyl)-1-Penten-3-One, · 4-(para-Methoxyphenyl)-2-Butanone, · 1-(para-Methoxyphenyl)-2-Propanone, · Methoxypyrazine, · Methyl 2-Furoate, · Methyl 2-Octynoate, · Methyl 2-Pyrrolyl Ketone, · Methyl Anisate, · Methyl Anthranilate, · Methyl Benzoate, · Methyl Cinnamate, · Methyl Dihydrojasmonate, · Methyl Ester of Rosin, Partially Hydrogenated, · Methyl Isovalerate, · Methyl Linoleate (48%), · Methyl Linolenate (52%) Mixture, · Methyl Naphthyl Ketone, · Methyl Nicotinate, · Methyl Phenylacetate, · Methyl Salicylate, · Methyl Sulfide, · 3-Methyl-1-Cyclopentadecanone, · 4-Methyl-1-Phenyl-2-Pentanone, · 5-Methyl-2-Phenyl-2-Hexenal, · 5-Methyl-2-Thiophenecarboxaldehyde, · 6-Methyl-3,-5-Heptadien-2-One, · 2-Methyl-3-(para-Isopropylphenyl) Propionaldehyde, · 5-Methyl-3-Hexen-2-One, · 1-Methyl-3Methoxy-4-Isopropylbenzene, · 4-Methyl-3-Pentene-2-One, · 2-Methyl-4-Phenylbutyraldehyde, · 6-Methyl-5-Hepten-2-One, · 4-Methyl-5-Thiazoleethanol, · 4-Methyl-5-Vinylthiazole, · Methyl-alpha-Ionone, · Methyl-trans-2-Butenoic Acid, · 4-Methylacetophenone, · para-Methylanisole, · alpha-Methylbenzyl Acetate, · alpha-Methylbenzyl Alcohol, · 2-Methylbutyraldehyde, · 3-Methylbutyraldehyde, · 2-Methylbutyric Acid, · alpha-Methylcinnamaldehyde, · Methylcyclopentenolone, · 2-Methylheptanoic Acid, · 2-Methylhexanoic Acid, · 3-Methylpentanoic Acid, · 4-Methylpentanoic Acid, · 2-Methylpyrazine, · 5-Methylquinoxaline, · 2-Methyltetrahydrofuran-3-One * (Methylthio)Methylpyrazine (Mixture Of Isomers), · 3-Methylthiopropionaldehyde, · Methyl 3-Methylthiopropionate, · 2-Methylvaleric Acid, · Mimosa Absolute and Extract, · Molasses Extract and Tincture, · Mountain Maple Solid Extract, · Mullein Flowers, · Myristaldehyde, · Myristic Acid, · Myrrh Oil, · beta-Napthyl Ethyl Ether, · Nerol, · Neroli Bigarde Oil, · Nerolidol, · Nona-2-trans,6-cis-Dienal, · 2,6-Nonadien-1-Ol, · gamma-Nonalactone, · Nonanal, · Nonanoic Acid, · Nonanone, · trans-2-Nonen-1-Ol, · 2-Nonenal, · Nonyl Acetate, · Nutmeg Powder and Oil, · Oak Chips Extract and Oil, · Oak Moss Absolute, · 9,12-Octadecadienoic Acid (48%) And 9,12,15-Octadecatrienoic Acid (52%), · delta-Octalactone, · gamma-Octalactone, · Octanal, · Octanoic Acid, · 1-Octanol, · 2-Octanone, · 3-Octen-2-One, · 1-Octen-3-Ol, · 1-Octen-3-Yl Acetate, · 2-Octenal, · Octyl Isobutyrate, · Oleic Acid , · Olibanum Oil, · Opoponax Oil And Gum, · Orange Blossoms Water, Absolute, and Leaf Absolute, · Orange Oil and Extract, · Origanum Oil, · Orris Concrete Oil and Root Extract, · Palmarosa Oil, · Palmitic Acid, · Parsley Seed Oil, · Patchouli Oil, · omega-Pentadecalactone, · 2,3-Pentanedione, · 2-Pentanone, · 4-Pentenoic Acid, · 2-Pentylpyridine, · Pepper Oil, Black And White, · Peppermint Oil, · Peruvian (Bois De Rose) Oil, · Petitgrain Absolute, Mandarin Oil and Terpeneless Oil, · alpha-Phellandrene, · 2-Phenenthyl Acetate, · Phenenthyl Alcohol, · Phenethyl Butyrate, · Phenethyl Cinnamate, · Phenethyl Isobutyrate, · Phenethyl Isovalerate, · Phenethyl Phenylacetate, · Phenethyl Salicylate, · 1-Phenyl-1-Propanol, · 3-Phenyl-1-Propanol, · 2-Phenyl-2-Butenal, · 4-Phenyl-3-Buten-2-Ol, · 4-Phenyl-3-Buten-2-One, · Phenylacetaldehyde, · Phenylacetic Acid, · 1-Phenylalanine, · 3-Phenylpropionaldehyde, · 3-Phenylpropionic Acid, · 3-Phenylpropyl Acetate, · 3-Phenylpropyl Cinnamate, · 2-(3-Phenylpropyl)Tetrahydrofuran, · Phosphoric Acid, · Pimenta Leaf Oil, · Pine Needle Oil, Pine Oil, Scotch, · Pineapple Juice Concentrate, · alpha-Pinene, beta-Pinene, · D-Piperitone, · Piperonal, · Pipsissewa Leaf Extract, · Plum Juice, · Potassium Sorbate, · 1-Proline, · Propenylguaethol, · Propionic Acid, · Propyl Acetate, · Propyl para-Hydroxybenzoate, · Propylene Glycol, · 3-Propylidenephthalide, · Prune Juice and Concentrate, · Pyridine, · Pyroligneous Acid And Extract, * * Pyrrole, * Pyruvic Acid, * Raisin Juice Concentrate, * Rhodinol, * Rose Absolute and Oil, * Rosemary Oil, * Rum, * Rum Ether, * Rye Extract, * Sage, Sage Oil, and Sage Oleoresin, * Salicylaldehyde, * Sandalwood Oil, Yellow, * Sclareolide, * Skatole, * Smoke Flavor, * Snakeroot Oil, * Sodium Acetate, * Sodium Benzoate, * Sodium Bicarbonate, * Sodium Carbonate, * Sodium Chloride, * Sodium Citrate, * Sodium Hydroxide, * Solanone, * Spearmint Oil, * Styrax Extract, Gum and Oil, * Sucrose Octaacetate, * Sugar Alcohols, * Sugars, * Tagetes Oil, * Tannic Acid, * Tartaric Acid, * Tea Leaf and Absolute, * alpha-Terpineol, * Terpinolene, * Terpinyl Acetate, * 5,6,7,8-Tetrahydroquinoxaline, * 1,5,5,9-Tetramethyl-13-Oxatricyclo(8.3.0.0(4,9))Tridecane, * 2,3,4,5, and 3,4,5,6-Tetramethylethyl-Cyclohexanone, * 2,3,5,6-Tetramethylpyrazine, * Thiamine Hydrochloride, * Thiazole, * 1-Threonine, * Thyme Oil, White and Red, * Thymol, * Tobacco Extracts, * Tochopherols (mixed), * Tolu Balsam Gum and Extract, * Tolualdehydes, * para-Tolyl 3-Methylbutyrate, * para-Tolyl Acetaldehyde, * para-Tolyl Acetate, * para-Tolyl Isobutyrate, * para-Tolyl Phenylacetate, * Triacetin, * 2-Tridecanone, * 2-Tridecenal, * Triethyl Citrate, * 3,5,5-Trimethyl -1-Hexanol, * para,alpha,alpha-Trimethylbenzyl Alcohol, * 4-(2,6,6-Trimethylcyclohex-1-Enyl)But-2-En-4-One, * 2,6,6-Trimethylcyclohex-2-Ene-1,4-Dione, * 2,6,6-Trimethylcyclohexa-1,3-Dienyl Methan, * 4-(2,6,6-Trimethylcyclohexa-1,3-Dienyl)But-2-En-4-One, * 2,2,6-Trimethylcyclohexanone, * 2,3,5-Trimethylpyrazine, * 1-Tyrosine, * delta-Undercalactone, * gamma-Undecalactone, * Undecanal, * 2-Undecanone, 1 * 0-Undecenal, * Urea, * Valencene, * Valeraldehyde, * Valerian Root Extract, Oil and Powder, * Valeric Acid, * gamma-Valerolactone, * Valine, * Vanilla Extract And Oleoresin, * Vanillin, * Veratraldehyde, * Vetiver Oil, * Vinegar, * Violet Leaf Absolute, * Walnut Hull Extract, * Water, * Wheat Extract And Flour, * Wild Cherry Bark Extract, * Wine and Wine Sherry, * Xanthan Gum, * 3,4-Xylenol, * Yeast Benzene 2-Napthylamine 4-Aminobiphenyl Nickel Polonium 210 (radioactive) Nitrogen oxides N-Nitrosodimethylamine N-Nitrosodiethylamine N-Nitrosopyrrolidine 1,3-Butadiene Analine Formaldehyde Hydrazine N-Nitrodiethanolamine Cadmium Benzo[a]pyrene Benz[a]anthracene Y-Butyrolactone Particulate matter N-Nitrosonornicotine NNK Carbon monoxide Carbon dioxide Carbonyl sulfide Toluene Acrolein Acetone Pyridine 3-Methylpyridine 3-Vinylpyridine Hydrogen cyanide Ammonia Methylamine Dimethylamine Nicotine Anatabine Phenol Catechol Hydorquinone Cholesterol Quinoline Harman Zinc Benzoic acid Lactic acid Glycolic acid Succinic acit PCDDs and PCDFs (Dioxins, Dibenzofurans) Formic acid Acetic acid Methyl chloride Dimethylnitrosamine Ethylmethylnitrosamine Nitrosopyrrolidine Hydrazine Vinyl Chloride Urethane Formaldehyde Carbon Monoxide Hydrogen Cyanide Acrolein Acetadehyde Nitrogen oxides Ammonia Pyridine Nitric acid Mathylamine Hydrogen cyanide Indole 3-hydroxypyridine 3-vinylpyridine Acetone Acetonitrile Acrolein 1,3-Butadiene, mg Nitrous acid isoquioline Isoamylamine 3-Cyanopyridine Carbonyls Formaldehyde, Acetaldehyde, Acetone, Acrolein, Propionaldehyde, Crotonaldehyde, Methyl-Ethyl-Ketone, Butyraldehyde Phenolics Hydroquinone, Resorcinol, Catechol, Phenol, Cresol (m+p and o) Benzo[a]pyrene BaP (HPLC) Aromatic Amines 3- and 4-aminobiphenyl, 1- and 2- aminonapthlene, o-toluidine, o-anisidine Oxides of Nitrogen NO, NOx Hydrogen Cyanide HCN (gas and particulate phases) Ammonia NH3 by ion chromatography Volatiles Benzene, Toluene, 1,3-butadiene, Isoprene, Acrylonitrile Semi-Volatiles Pyridine, Quinoline, Styrene Trace Metals Nickel (Ni) Cadmium (Cd) Lead (Pb) Chromium (Cr) Arsenic (As) Selenium (Se) Mercury Mercury (Hg) Smoke pH Integrated Puff Profile Tobacco Specific Nitrosamines N-Nitrosonornicotine (NNN) N-Nitrosoanabasine (NAB) N-Nitrosoanatabine (NAT) 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) Volatile Nitrosamines N,N-Nitrosodimethylamine (NDMA) N-Nitrosopyrrolidine (NPYR) N,N-Nitrosodiethylamine (NDEA) N,N-Nitrosoethylmethylamine (NEMA) N,N-Nitrosodipropylamine (NDPA) N,N-Nitrosodibuthylamine (NDBA) N-Nitrosopiperidine (NPIP) Polycyclic Aromatic Hydrocarbons Naphthalene 1-Methylnaphthalene 2-methylnaphthalene Acenaphthylene Acenaphthene Fluorene Phenanthrene Anthracene Fluoranthene Pyrene Benzo(a)anthracene Chrysene Benzo(b)fluoranthene Benzo(k)fluoranthene Benzo(j)fluoranthene Benzo(g,h,l)perylene Benzo(e)pyrene Benzo(a)pyrene Perylene Indeno(1,2,3,-cd)pyrene Dibenzo(a,h)anthracene Dibenz(a,j)acridine Dibenz(a,h)acridine Dibenz(a,e)pyrene Dibenz(a,h)pyrene Dibenz(a,i)pyrene Dibenz(a,l)pyrene 7H-Dibenzo(c,g)carbazole Heterocyclic Aromatic Amines 2-Amino-3-methylimidaszo(4,5-f)quinoline (IQ) 2-Amino-3,4-dimethylimidazo(4,5-f)quinoline (MeIQ) 2-Amino-3-methyl-9H-pyrido(2,3-b)indole (MeAaC) 2-Amino-9H-pyrido(2,3-b)indole (AaC) 1-Methyl-9H-pyridol(3,4-b)indole (Harman) 9H-Pyrido(3,4-b)indole (Norharman) Nitrogen 280-320 mg (56-64%b) Oxygen 50-70 mg (11-14%b) Carbon dioxide 45-65 mg (9-13%b) Carbon monoxide 14-23 mg (2.8-4.6%b) Water 7-12 mg (1.4-2.4%b) Argon 5mg (1.0%b) Hydrogen 0.5-1.0 mg Ammonia 10-130 μg Nitrogen oxides (NOx) 100-600 μg Hydrogen cyanide 400-500 μg Hydrogen sulfide 20-90 μg Methane 1.0-2.0 mg Other volatile alkanes (20) 1.0-.16 mgc Volatile alkenes (16) 0.4-0.5mg Isoprene 0.2-0.4mg Butadiene 25-40μg Acetylene 20-35μg Benzene 12-50μg Toluene 20-60μg Styrene 10μg Other volatile aromatic hydrocarbons (29) 15-30μg Acetic acid 300-1,700 μg Propionic acid 100-300 μg Methyl formate 20-30 μg Other volatile acids (6) 5-10 μgc Formaldehyde 20-100 μg Acetaldehyde 400-1,400 μg Acetone Other volatile ketones (3) Methanol Other volatile alcohols (7) Acetonitrile Other volatile nitriles (I0) Furan Other volatile furans (4) Pyridine Picolines (3) 3-Vinylpyridine Other volatile pyridines (25) Pyrrole Pyrrolidine N-Methylpyrrolidine Volatile pyrazines (18) Methylamine Other aliphatic amines (32) Nornicotine Anatabine Anabasine Other tobacco alkaloids (17) Bipyridyls (4) n-Hentriacontane (n-C31H64) Total nonvolatile hydrocarbons (45)b Naphthalene Other naphthalenes (23) Phenanthrenes (7) Palmitic acid 100-150 Stearic acid 50-75 Oleic acid 40-110 Linoleic acid 60-150 Linolenic acid 150-250 Lactic acid 60-80 Indole 10-15 Skatole 12-16 Other indoles (13) NA Quinolines (7) 2-4 Other N-heterocyclic hydrocarbons (55) NA Benzofurans (4) 200-300 Other O-heterocyclic hydrocarbons (42) NA Stigmasterol 40-70 Sitosterol 30-40 Campesterol 20-30 Cholesterol 10-20 Aniline 0.36 Toluidines 0.23 Other aromatic amines (12) 0.25 Tobacco-specific N-nitrosamines (4)c 0.34-2.7 Glycerol PAH Benz(a)anthracene Benzo(b)fluoranthene Benzo(j)fluoranthene Benzo(k)fluoranthene Benzo(a)pyrene Chrysene Dibenz(a,h)anthracene Dibenzo(a,1)pyrene Dibenzo(a,1)pyrene Indeno(1,2,3-c,d)pyrene 5-Methylchrysene Aza-arenes Quinoline Dibenz(a,h)acridine Dibenz(aj)acridine 7H-Dibenzo(c,g)carbazole N-Nitrosamines N-Nitrosodimethylamine N-Nitrosoethyl methylamine N-Nitrosodiethylamine N-Nitrosopyrrolidine N-Nitrosodiethanolamine N’-Nitrosonomicotine 4-(Methylnitrosamino)-1- (3-pyridyl)-1-butanone N’-Nitrosoanabasine N-Nitrosomorpholine 2-Toluidine 2-Naphthylamine 4-Aminobiphenyl Aldehydes Formaldehydea Acetaldehydea Crotonaldehyde Miscellaneous organic compounds Benzene Acrylonitrile 1,1-Dimethylhydrazine 2-Nitropropane Ethylcarbamate Vinylchloride Inorganic compounds Hydrazine Arsenic Nickel Chromium Cadmium Lead Polonium-210 Asbestos Plutonium

The Rest of the Story

This example shows how absurd the regulatory approach taken by the FDA legislation is. The reality is that the FDA is not going to know whether or not its proposed changes to cigarette components are going to make cigarettes safer or not. So the FDA is going to use smokers as guinea pigs to figure that out. Now that may be fine; however, in the mean time, people are going to be given the implied message that cigarettes are safer. In other words, the fraud that the tobacco companies were found guilty of committing against American consumers by implying a safer product without documentation will now be transferred over to the United States government.

I don't think we want any part of this regulatory scheme.

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